The Center for Wellness

The Center for Wellness

1258 Mann Drive
Matthews, North Carolina 28105

Mark O'Neal Speight, M.D. - Matthews NC Bioidentical Hormone Doctor

Matthews NC Bioidentical Hormone Doctor Mark O'Neal Speight, M.D. at The Center For Wellness has almost 20 years of experience practicing medicine. Dr. Speight strives to help you achieve optimal health and hormone balance through a preventive, nutritional, and environmental approach to medicine. He offers the most advanced solutions to 21st century health challenges while maintaining focus on his patient’s individual and unique needs. He gives each individual respect, compassion, and the confidentiality they deserve. Dr. Speight aims to optimize disease prevention through an ongoing dedication to uncovering the most innovative and validated therapies in medicine, including Bioidentical Hormone Replacement Therapy. Through years of determined research and collaboration with nutritionists, physicians, and researchers from all over the world, his goal has been and remains: to provide advanced medical solutions of the highest caliber in solving the complex health disorders of our time.


  • Anti-Aging Skincare Treatments
  • Class Iv High Powered Healing Laser
  • Healing Laser Therapy
  • SkinPen
  • Chelation Therapy
  • Special Laboratory Services
  • Thermography
  • Bioidentical Hormone Replacement Therapy
  • Hyperbaric Oxygen Therapy
  • Medical Testing
  • Pharmaceutical Grade Supplements


“Dear. Dr. Speight, I just wanted you to know how blessed I am to have a doctor who has gone the extra mile for his patients. I am 72 years of age and have been to sleep studies and several doctors in different states and I felt uneasy with all of them but two. You have been able to answer my questions and help me with bioidentical hormones and much more. I wanted to let you know that I am sleeping better, have more confidence, have a healthier sense of well-being and feeling younger again. Each day is a good day to live. You don’t always tell me what I want to hear, but I have learned to trust you. Thank you.”